HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → HCID 86741148, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1,2,3,4-Tetrahydro-Beta-Carboline-3-Carboxylic Acid | HCID 98285 | — |
| Reactant | N,N-Dimethylaminoethyl chloride hydrochloride | HCID 11636816 | — |
| Product | HCID 86741148 | HCID 86741148 | — |
Reaction Steps
In the same manner as described in Example 6, (3RS)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (2.16 g), 10N NaOH (2 ml), dimethylsulfoxide (6 ml), carbon disulfide (912 mg) and 2-(dimethylamino)ethyl chloride hydrochloride (1.73 g) are reacted. The precipitates are collected by filtration, washed with water and ethanol, and then dried to give the title compound (3.11 g, quantitatively) as yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04628057 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-6256f36677f5454fa4e95d5e9eb66848 |
| Source note | uspto-grants-1986_12 |