HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → HCID 13561928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1,2,3,4-Tetrahydro-Beta-Carboline-3-Carboxylic Acid | HCID 98285 | — |
| Product | HCID 13561928 | HCID 13561928 | 65% |
Reaction Steps
In the same manner as described in Example 6, (3RS)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (2.16 g), 10N NaOH (2 ml), dimethylsulfoxide (6 ml), carbon disulfide (912 mg) and ethyl bromoacetate (2.0 g) are reacted. The product is recrystallized from ethanol to give the title compound (1.41 g, 65%) as colorless needles, m.p. 190°-192° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04628057 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-c2b9e047f0b14946ac5504339c8a0d56 |
| Source note | uspto-grants-1986_12 |