HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Disulfide → HCID 13561939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1,2,3,4-Tetrahydro-Beta-Carboline-3-Carboxylic Acid | HCID 98285 | — |
| Reactant | 4-Methoxybenzyl bromide | HCID 165021 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13561939 | HCID 13561939 | 79% |
Reaction Steps
In the same manner as described in Example 16, (3RS)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (4.32 g), 10N NaOH (4 ml), carbon disulfide (1.4 ml), dimethylsulfoxide (20 ml) and 4-methoxybenzyl bromide (4.02 g) are reacted and treated. The product is crystallized from isopropyl ether to give the title compound (6.50 g, 79%) as colorless needles, m.p. 195°-196° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04628057 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-be7db92f534844cd9321ce37b73d5ce3 |
| Source note | uspto-grants-1986_12 |