HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Disulfide → HCID 13561940, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | 1,2,3,4-Tetrahydro-Beta-Carboline-3-Carboxylic Acid | HCID 98285 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13561940 | HCID 13561940 | 54% |
Reaction Steps
In the same manner as described in Example 16, (3RS)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (4.22 g), 10N NaOH (3.9 ml), carbon disulfide (1.4 ml), dimethylsulfoxide (12 ml) and 4-nitrobenzyl bromide (4.63 g) are reacted and treated. The product is crystallized from ethanol to give the title compound (4.7 g, 54%) as yellow crystals, m.p. 194°-195° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04628057 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-66b7b17879ad4379be31e336188b4650 |
| Source note | uspto-grants-1986_12 |