HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Disulfide → HCID 13561942, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(Bromomethyl)benzoic acid | HCID 22599 | — |
| Reactant | 1,2,3,4-Tetrahydro-Beta-Carboline-3-Carboxylic Acid | HCID 98285 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13561942 | HCID 13561942 | 57.7% |
Reaction Steps
In the same manner as described in Example 16, (3RS)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (1.08 g), 10N NaOH (1.5 ml), carbon disulfide (456 mg), dimethylsulfoxide and 4-bromomethylbenzoic acid (1.29 g) are reacted and treated. The product is crystallized from chloroform to give the title compound (1.23 g, 53%), m.p. 152°-153° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04628057 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-e456381c4eb14d6682d6e331c06eb8a6 |
| Source note | uspto-grants-1986_12 |