Methyl iodide → HCID 86741152, compound

Participants

Reaction Steps

In the same manner as described in Example 43, (1RS,3SR)-trans-1-n-butyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (1.2 g), triethylamine (1.02 g), carbon disulfide (0.39 g), methyl iodide (0.72 g), methanol (14 ml) and water (2 ml) are reacted and treated. The product is recrystallized from aqueous ethanol to give the title compound (1.2 g, 75%), m.p. 99°-102° C. (decomp.).

Provenance & Evidence