Methyl iodide → HCID 86741153, compound

Participants

Reaction Steps

In the same manner as described in Example 43, (1RS,3SR)-trans-1-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (1.48 g), triethylamine (1.68 ml), carbon disulfide (0.73 ml), methyl iodide (0.75 ml) and 80% methanol (20 ml) are reacted and treated. The product is crystallized from aqueous ethanol to give the title compound (0.68 g), m.p. 187°-188° C. (decomp.).

Provenance & Evidence