D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid → ethyl (3R)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylate

Participants

Role	Name	HCID	Charge
Reactant	D-1,2,3,4-Tetrahydronorharman-3-carboxylic acid	HCID 675102	—
Reactant	ethyl (3S)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylate	HCID 1079579	—
Product	ethyl (3R)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylate	HCID 7223904	54%

Reaction Steps

In the same manner as described above (1) using (3R)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, there is obtained the title compound (54%) as colorless needles, m.p. 126°-128° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04628057
Source dataset	uspto-grants-1986_12
ORD ID	ord-a20e568fc46745fda79e67da936dd249
Source note	uspto-grants-1986_12