Thionyl Chloride → HCID 13281512, compound

Participants

Reaction Steps

A solution of 5-carboxymethylamino-1-(2-chloro-4-trifluoromethylphenyl)-4-cyanopyrazole (4.5 g; prepared as described in Example 26) in thionyl chloride (40 ml) was heated at reflux for 1 hour. The reaction mixture was cooled and evaporated under diminished pressure to give 5-chlorocarbonylmethylamino-1-(2-chloro-4-trifluoromethylphenyl)-4-cyanopyrazole (4.72 g), in the form of a red oil, which was used immediately in b or c below:

Provenance & Evidence