HCID 13127534, compound → HCID 13127589, compound

HRID 1249125Notes

Reaction equation

HRID 1249125 reaction equation
[C:1]([C:3]1[CH:4]=[N:5][N:6]([C:27]2[CH:32]=[CH:31][C:30]([Cl:33])=[C:29]([Cl:34])[C:28]=2[Cl:35])[C:7]=1[N:8](C(OC1C=CC=CC=1)=O)[C:9]([O:11][C:12]1C=CC=CC=1)=[O:10])#[N:2]>CO>[C:1]([C:3]1[CH:4]=[N:5][N:6]([C:27]2[CH:32]=[CH:31][C:30]([Cl:33])=[C:29]([Cl:34])[C:28]=2[Cl:35])[C:7]=1[NH:8][C:9]([O:11][CH3:12])=[O:10])#[N:2]

Participants

3

Reactant 1

HCID 13127534HCID 13127534, compound

Product 1

HCID 13127589HCID 13127589, compoundYield 58.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A stirred mixture of 4-cyano-5-di(phenoxycarbonyl)amino-1-(2,3,4-trichlorophenyl)pyrazole (30 g) in methanol (600 ml) was heated at reflux for 80 hours. After cooling the reaction mixture was evaporated and the residue was suspended in dichloromethane (250 ml). The insoluble material was filtered off to give 4-cyano-5-methoxycarbonylamino-1-(2,3,4-trichlorophenyl)pyrazole (11.5 g), m.p. 205°-207° C., in the form of a colourless solid.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 80 hours
  3. temperatureAfter cooling the reaction mixture
  4. customwas evaporated
  5. filtrationThe insoluble material was filtered off

Sources & evidence

ORD record
ord-fae67c0ace114a4dbae833d7419f3ef5
Source dataset
uspto-grants-1986_12
Patent number
US04629495

Reaction notes

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