4-[(Methylsulfonyl)amino]benzoyl chloride → N-[2-((2-(3,4-Dimethoxyphenyl)ethyl)amino)ethyl]-4-[(methylsulfonyl)amino]-benzamide hydrochloride
Reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([Cl:12])=[O:11])=[CH:8][CH:7]=1)(=[O:4])=[O:3].[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH2:25][CH2:26][NH:27][CH2:28][CH2:29][NH2:30])[CH:20]=[CH:21][C:22]=1[O:23][CH3:24]>>[ClH:12].[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH2:25][CH2:26][NH:27][CH2:28][CH2:29][NH:30][C:10](=[O:11])[C:9]2[CH:13]=[CH:14][C:6]([NH:5][S:2]([CH3:1])(=[O:4])=[O:3])=[CH:7][CH:8]=2)[CH:20]=[CH:21][C:22]=1[O:23][CH3:24]Participants
3
Procedure
In a manner similar to Example XVII, react 4-[(methylsulfonyl)amino]benzoyl chloride with N-[2-(3,4-dimethoxyphenyl)ethyl]-1,2-ethanediamine to obtain the title compound.
Sources & evidence
- ORD record
- ord-3b93c2efb380421990066692e4f0d92a
- Source dataset
- uspto-grants-1986_12
- Patent number
- US04629739
Reaction notes
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