Ammonia → HCID 20225211, compound
Reaction equation
[C:1]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH:14]([NH:16][CH2:17][CH:18]([O:26][CH3:27])[C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([Cl:25])[CH:20]=2)[CH3:15])=[CH:9][CH:8]=1)(OC)=[O:2].[NH3:28]>>[NH2:28][C:1]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH:14]([NH:16][CH2:17][CH:18]([O:26][CH3:27])[C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([Cl:25])[CH:20]=2)[CH3:15])=[CH:9][CH:8]=1)=[O:2]Participants
3
Procedure
The title compound was prepared, as an oil, from N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-methoxy-2-(3-chlorophenyl)ethanamine and 0.88 ammonia, by an analogous procedure to that described in Example 4. The product was used in Example 24 without further purification.
Workup
- customThe product was used in Example 24 without further purification
Sources & evidence
- ORD record
- ord-eda0df54779047be95b7cd20d677ff66
- Source dataset
- uspto-grants-1986_12
- Patent number
- US04629737
Reaction notes
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