HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 3-(N-octanoylglycylglycyloxy)octadecanoic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | N-octanoylglycylglycine | HCID 312837 | — |
| Reactant | Tert-butyl 3-hydroxyoctadecanoate | HCID 13962663 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(N-octanoylglycylglycyloxy)octadecanoic acid tert-butyl ester | HCID 54423126 | 29.6% |
Reaction Steps
1.96 g of 3-hydroxyoctadecanoic acid tert-butyl ester and 1.43 g of N-octanoylglycylglycine were mixed with 40 ml of methylenechloride. By following the same procedure as in Example 23-(i) after adding 60 mg of DMAP and 1.14 g of DCC, 970 mg of 3-(N-octanoylglycylglycyloxy)octadecanoic acid tert-butyl ester was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04629736 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-e852c88a226c46ac94471dd9c594483b |
| Source note | uspto-grants-1986_12 |