HCID 54024474, compound → HCID 53809364, compound

Participants

Reaction Steps

Precipitates thus formed were removed by filtration, the filtrate was washed with water, dried over anhydrous magnesium sulfate, concentrated, and subjected to silica gel column chromatography. The product was eluted with ethyl acetate-chloroform (1:9--1:1 by v/v ratio) to provide 600 mg of (S)-3-(6-decanamidohexanamido)-3-tetradecylcarbamoylpropionic acid benzyl ester. 1.00 g of the ester compound obtained was dissolved in a mixture of 30 ml of tetrahydrofuran and 10 ml of methanol and after carrying out catalytic reduction by using 100 mg of 10% Pd-C and removing the catalyst by filtration, the solvent was distilled off to provide 670 mg of (S)-3-(6-decanamidohexanamido)-3-tetradecylcarbamoylpropionic acid.

Provenance & Evidence