反应详情

2.1 g of (S)-3-amino-3-tetradecylcarbamoylpropionic acid benzyl ester and 1.5 g of 6-(6-acetamidohexanamido)hexanoic acid were mingled in 10 ml of methylene chloride and after adding thereto 1.1 g of DCC and treating the mixture in the same manner as in Example 26, the product was subjected to silica gel column chromatography, and was eluted with methanol-chloroform (1:3 by v/v ratio) to provide 250 mg of (s)-3-[6-(6-acetamidohexanamido)hexanamido]-3-tetradecylcarbamoylpropionic acid benzyl ester.

1. additionafter adding
2. washwas eluted with methanol-chloroform (1:3 by v/v ratio)