HRID1249224

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCCCCCCCCCCNC(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)CCCCCNC(=O)CCCCCNS(C)(=O)=O

HCID54041120

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCNC(=O)[C@H](CC(=O)O)NC(=O)CCCCCNC(=O)CCCCCNS(C)(=O)=O

HCID53989773

未命名化合物

收率 359%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

35 mg of the ester compound thus obtained was dissolved in 10 ml of methanol and after treating the mixture in the same manner as in Example 26, 110 mg of (S)-3-[6-(6-methanesulfonamidohexanamido)hexanamido]-3-tetradecylcarbamoylpropionic acid was obtained.

WORKUP

后处理

additionafter treating the mixture in the same manner as in Example 26

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a2cd63468c1f44e5adb8b71074dfd812
来源数据集: uspto-grants-1986_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04629736
来源说明: uspto-grants-1986_12

反应 SMILES

C([O:8][C:9](=[O:50])[CH2:10][C@H:11]([NH:29][C:30](=[O:49])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][NH:36][C:37](=[O:48])[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][NH:43][S:44]([CH3:47])(=[O:46])=[O:45])[C:12](=[O:28])[NH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])C1C=CC=CC=1>CO>[CH3:47][S:44]([NH:43][CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][C:37]([NH:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][C:30]([NH:29][C@H:11]([C:12](=[O:28])[NH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:10][C:9]([OH:50])=[O:8])=[O:49])=[O:48])(=[O:46])=[O:45]