HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-dihydro-2H-pyran → HCID 14823513, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Pyridine 4-methylbenzene-1-sulfonate | HCID 161440 | — |
| Reactant | HCID 13813833 | HCID 13813833 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14823513 | HCID 14823513 | — |
Reaction Steps
1 g Ethyl 2-(4-chloro-3-hydroxybutanamido)acetate is dissolved in 10 ml CH2Cl2. 100 mg pyridine p-toluenesulphonate and 0.5 ml dihydropyran are added. The mixture is stirred for 7 h. The solvent is evaporated and the residue chromatographed, eluting with ethyl acetate. A colourless oil is obtained, Rf 0.5 (silica gel plates, thickness 0.25 mm, eluent ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04629797 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-c10eb838a8ce4ebe995e79021f7ecfdf |
| Source note | uspto-grants-1986_12 |