HCID 11267230, compound → HCID 86741165, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 4-(2,4-dinitrophenoxy)-phenyldiazomethane in CH2Cl2 (20 ml) is added to a solution of Boc-dehydroalanine-p-nitrobenzyl ester (2) in 20 ml CH2Cl2 at -15° C. After stirring 1 hr at -15° C. and 4 hr at 25°, the solution is evaporated to dryness and the residue is triturated with hexane. The solid product, p-nitrobenzyl 3-t-butoxycarbonylamino-5-(4-[2,4-dinitrophenoxyl]-phenyl)-pyrazoline-3-carboxylate (18), is recrystallized from ethyl acetate-hexane to constant melting point. NMR (CDCl3)δ: 4.8-5.4 (m, 1H, CH--N=N).

Provenance & Evidence