Acetic Acid → HCID 136026289, compound

Participants

Reaction Steps

3-Hydroxy-5-(3-pyridyl)-2-butyrylcyclohex-2-en-1-one (1.0 g) was stirred with O-ethylhydroxylamine hydrochloride (1.1 equiv) and sodium acetate trihydrate (1.1 equiv) in ethanol (30 ml) at room temperature for 12 hr. The mixture was poured into a dilute acetic acid solution, which was subsequently extracted with ether. The dried (MgSO4) organic extract was evaporated to give 2-[1-(ethoxyimino)-butyl]-3-hydroxy-5-(3-pyridyl)cyclohex-2-en-1-one as an oil.

Provenance & Evidence