Diethyl Ether → HCID 13782559, compound

Participants

Reaction Steps

A mixed solution of methyl iodide (23.90 g, 0.16 moles)/dried diethyl ether (10 ml) was dropped into a mixture of magnesium (2.90 g, 0.12 moles)/dried diethyl ether (20 ml) in 1 hour while stirring under water-cooling conditions. The mixture was stirred for 48 hours at room temperature and subjected to separation by filtration. Into the resulting filtrate was dropped a mixed solution of 2,2,7,7-tetramethylcycloheptanone (16.80 g, 0.10 mole)/dried diethyl ether (30 ml) in 30 minutes while stirring at room temperature. The mixture was stirred at room temperature for 48 hours. The resulting reaction mixture was treated in the same manner as in Example 1 to obtain 10.20 g (yield 55.3%) of the captioned compound. This compound was a white solid having a woody, earthy camphoraceous and patchuli oil-like odor.

Provenance & Evidence