p-Toluenesulfonic acid → HCID 14178040, compound

Participants

Reaction Steps

Into a 250 cc reaction flask equipped with stirrer, thermometer, reflux condenser and heating mantle are placed 26.5 grams of 2-mercapto propionic acid (0.25 moles); 58 grams allyl alcohol (1.0 moles) and 0.2 grams of para-toluene sulfonic acid. With stirring, the reaction mass is heated to reflux and maintained at reflux for a period of 8 hours. At the end of the 8 hour period, the reaction mass is cooled to room temperature and transferred to a separatory funnel. The reaction mass is then extracted with two 250 ml portions of methylene dichloride. The methylene dichloride extracts are combined and washed with one 100 ml portion of saturated sodium carbonate solution followed by one 100 ml portion of saturated sodium chloride solution. The resulting organic material is dried over anhydrous sodium sulfate, filtered and distilled on a micro Vigreux column yielding the following fractions:

Provenance & Evidence