HCID 14456189, compound → HCID 14456190, compound

Participants

Reaction Steps

Ethyl-3-(4-ethoxymethylindol-3-yl)-4-methoxy-2-nitrobutyrate (11.1 g) in ethanol (350 ml) was catalytically hydrogenated with Raney-nickel at room temperature under atmospheric pressure. The product obtained after filtration of the catalyst and evaporation of the solvent, was dissolved in a mixture of diethylether and ethylacetate. The solution was treated with water and evaporated. 8 g of oily ethyl-2-amino-3-(4-ethoxymethylindol-3-yl)-4-methoxybutyrate were obtained.

Provenance & Evidence