2-Mepp → HCID 13603438, compound

HRID 1249376Notes

Reaction equation

HRID 1249376 reaction equation
[O:1]1[CH2:15][CH:2]1[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12](=[O:14])[CH3:13])=[CH:7][CH:6]=1.[CH3:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[CH2:11]([C:8]1[CH:9]=[CH:10][C:5]([O:4][CH2:3][CH:2]([OH:1])[CH2:15][N:26]2[CH2:27][CH2:28][N:23]([C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=3[CH3:16])[CH2:24][CH2:25]2)=[CH:6][CH:7]=1)[C:12](=[O:14])[CH3:13]

Participants

3

Reactant 2

HCID 919652-MeppHCID 13603435HCID 13603435, compound

Product 1

HCID 13603438HCID 13603438, compound

Procedure

4-(2,3-Epoxypropoxy)-phenylacetone is reacted with 2-methylphenyl-piperazine analogously to Example 2(a). 1-[4-(propan-2-on-yl)-phenoxy]-3-[4-(2-methylphenyl)-piperazin-1-yl]-propan-2-ol is obtained.

Sources & evidence

ORD record
ord-13ba9c469b364339baf5d3b434a2d8e5
Source dataset
uspto-grants-1986_12
Patent number
US04631281

Reaction notes

Loading…