Water → HCID 13532503, compound

HRID 1249397Notes

Reaction equation

HRID 1249397 reaction equation
[Cl:1][C:2]1[CH:18]=[CH:17][C:5]([CH2:6][O:7][C:8]([CH3:16])([C:10](OC)([O:12]C)[CH3:11])[CH3:9])=[CH:4][CH:3]=1.O>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][O:7][C:8]([CH3:9])([CH3:16])[C:10](=[O:12])[CH3:11])=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 962WaterHCID 13532502HCID 13532502, compound

Product 1

HCID 13532503HCID 13532503, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

134 g (0.5 mol) of 2-(4-chlorobenzyloxy)-3,3-di- methoxy-2-methyl-butane are stirred in 1 liter of toluene with 100 g of ion exchanger (Levatit SP C118) and 200 ml of water at 60° C. for 8 hours. After the ion exchanger has been filtered off with suction, the organic phase is separated off, washed with water and concentrated in vacuo. The residue is distilled. 98 g (87% of theory) of 3-(4-chlorobenzyloxy)-3-methyl-2-butanone of boiling point 95° C. to 100° C./0.03 mm Hg are obtained.

Workup

  1. filtrationAfter the ion exchanger has been filtered off with suction
  2. customthe organic phase is separated off
  3. washwashed with water
  4. concentrationconcentrated in vacuo
  5. distillationThe residue is distilled

Sources & evidence

ORD record
ord-6a5263baa2894d1bbf03a51bb9dbc3bd
Source dataset
uspto-grants-1986_12
Patent number
US04631288

Reaction notes

Loading…