Potassium Hydroxide → HCID 13772948, compound

Participants

Reaction Steps

A hot solution of 8.2 g of potassium hydroxide in 155 ml of 3A ethanol was added to a hot solution of 18.7 g of 5-cyano-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid, ethyl ester in 315 ml of 3A ethanol. The salt that precipitated out of solution was dissolved in 2 l. of hot water and acidified with hydrochloric acid. The solid was collected by filtration and dried to afford 16.24 g of 5-cyano-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid. mp=209°-211° C.

Provenance & Evidence