2-Amino-4-methoxy-6-methyl-1,3,5-triazine → HCID 13769574, compound

Participants

Reaction Steps

A solution of 119 g of the compound of Example 6 in 100 ml dichloromethane was added over 0.25 hours to a suspension of 57 g of 4-methoxy-6-methyl-1,3,5-triazin-2-amine in 1000 ml dichloromethane. The reaction was heated at reflux for 3 to 4 hours, then stirred overnight at ambient temperature. The reaction mixture was filtered and dried. The crude product was dissolved in 2000 ml boiling dichloromethane, the solution filtered, and the filtrate evaporated in vacuo to give 75 g of the title compound, m.p. 183°-186° C.

Provenance & Evidence