Hydrogen Bromide → 5-(4-Aminophenyl)-6-methylpyrazin-2(1H)-one--hydrogen bromide (1/1)

Participants

Reaction Steps

5-(4-Benzyloxycarbonylaminophenyl)-6-methyl-2(1H)-pyrazinone (0.5 g) was treated with hydrogen bromide in acetic acid in a manner similar to that described in Description 3 to give the title compound as its hydrobromide salt (340 mg) which after digestion with hot ethanol had m.p.>300° C.; δ(D2O) inter alia 2.39 (3H, d, CH3), 8.03 (1H, q, pyrazinone ring 3-H); ν(KBr) 1705, 1750 cm-1.

Provenance & Evidence