4-[2,2-Bis(4-fluorophenyl)ethenyl]piperidine → 4-[2,2-Bis(4-fluorophenyl)ethyl]piperidine

HRID 1249567Notes

Reaction equation

HRID 1249567 reaction equation
Cl.C1(C(C2C=CC=CC=2)CC2CCNCC2)C=CC=CC=1.[F:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([C:37]2[CH:42]=[CH:41][C:40]([F:43])=[CH:39][CH:38]=2)=[CH:30][CH:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)=[CH:25][CH:24]=1>CCCCCC>[F:43][C:40]1[CH:41]=[CH:42][C:37]([CH:29]([C:26]2[CH:25]=[CH:24][C:23]([F:22])=[CH:28][CH:27]=2)[CH2:30][CH:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)=[CH:38][CH:39]=1

Participants

4

Reactant 2

HCID 137545034-[2,2-Bis(4-fluorophenyl)ethenyl]piperidineHCID 137545114-(2,2-diphenylethyl)piperidine HCl

Product 1

HCID 150203614-[2,2-Bis(4-fluorophenyl)ethyl]piperidine

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

The title compound was prepared in the same manner as 4-(2,2-diphenylethyl)piperidine HCl starting from 4-[2,2-bis(4-fluorophenyl)ethenyl]piperidine, 0.15 molar hexane solvate. The resulting clear, colorless, oil was used directly in the next steps.

Sources & evidence

ORD record
ord-842ff6d90e6241a499f4dbe3662a163b
Source dataset
uspto-grants-1986_12
Patent number
US04632925

Reaction notes

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