HCID 178456436, compound → HCID 53945269, compound

HRID 1249736Notes

Reaction equation

HRID 1249736 reaction equation
[CH:1]([N:4]1[C:8]([C:9]2[CH:14]=[CH:13][NH:12][C:11](=S(=O)=O)[N:10]=2)=[C:7]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[N:6]=[CH:5]1)([CH3:3])[CH3:2].[CH:25]1([N:31]2C(C3C=CNC(=S(=O)=O)N=3)=C(C3C=CC(F)=CC=3)N=C2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[CH:1]([N:4]1[C:8]([C:9]2[CH:14]=[CH:13][N:12]=[C:11]([NH:31][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[N:10]=2)=[C:7]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[N:6]=[CH:5]1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 178456436HCID 178456436, compoundHCID 178527381HCID 178527381, compound

Product 1

HCID 53945269HCID 53945269, compound

Procedure

The reaction was conducted in a manner analogous to Example 2d except substituting polymer-bound 1-isopropyl-4-(4-fluorophenyl)-5-[(2-sulfonyl)pyrimidin-4-yl]imidazole for polymer-bound 1-cyclohexyl-4-(4-fluorophenyl)-5-[(2-sulfonyl)pyrimidin-4-yl]imidazole: ESMS m/z=374 (MH)+

Sources & evidence

ORD record
ord-aa5a09b4c39443d9a8e56b9b00238e84
Source dataset
uspto-grants-2002_01
Patent number
US06335340B1

Reaction notes

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