反应详情

温度

140 °C

A mixture of 6-amino-benzo[1,3]dioxole-5-carboxylic acid (4.3 g, 23.7 mmol) and formamide (15 mL) was heated to 140° C. for 2 hours, then to 170° C. for 2 hours. After cooling to room temperature, precipitate was collected to give 7H-[1,3]dioxolo[4,5-g]quinazolin-8-one (1.11 g, 27%).

1. temperatureAfter cooling to room temperature
2. customprecipitate was collected