HCID 18328990, compound → HCID 9817343, compound

Participants

Reaction Steps

Potassium tert-butoxide (269 mg; 2.39 mmol) is added to a solution of 2-acetyl-1,1-dimethyl-6-methoxy-1,2,3,4-tetrahydro-β-carboline (164 mg; 0.60 mmol) in DMF (15 ml). The mixture is stirred under an oxygen atmosphere overnight. A 1/1 ethyl acetate/methanol mixture (10 ml) is then added. After evaporating the solvent and washing the solid, 2-acetyl-3,3-dimethyl-7-methoxy-9-oxo-1,3,4,9-tetrahydropyrrolo[3,4-b]quinoline is obtained (38 mg; 22%)

Provenance & Evidence