HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methoxymethyl-3-benzyloxy-6-methyl-pyran-4(1H)-one → 2-Methoxymethyl-3-benzyloxy-pyran-4(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methoxymethyl-3-benzyloxy-6-methyl-pyran-4(1H)-one | HCID 11747336 | — |
| Reactant | 2-(Hydroxymethyl)-3-(phenylmethoxy)-4H-pyran-4-one | HCID 21792545 | — |
| Product | 2-Methoxymethyl-3-benzyloxy-pyran-4(1H)-one | HCID 18678803 | 100% |
Reaction Steps
In an analogous procedure in the preparation of 2-methoxymethyl-3-benzyloxy-6-methyl-pyran-4(1H)-one using 2-hydroxymethyl-3-benzyloxy-pyran-4(1H)-one (2.32 g, 10 mmol, 1 eq.) yielded the title compound as an orange oil (2.5 g, ˜100%). Further purification by column chromatography on silica gel (eluant: EtOAc) furnished the pure product as a bright yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06335353B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-2a1fea1969a34817abb518445c41f829 |
| Source note | uspto-grants-2002_01 |