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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 124985Generated: October 25, 2026

Ammonium → 3-Chloro-4-[(2,5-difluorophenyl)-hydroxymethyl]pyridine

https://huagongshe.com/reaction/124985

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
ReactantEthyl AcetateHCID 8857—
Reactant3-ChloropyridineHCID 12287—
Reactant2,5-DifluorobenzaldehydeHCID 137663—
ReactantButyllithiumHCID 178418339—
Product3-Chloro-4-[(2,5-difluorophenyl)-hydroxymethyl]pyridineHCID 23114654—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-8f297b78ec524734b8a39d1a0dab853c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)