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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1249886Generated: October 25, 2026

Ethanol → 1-(Naphthalen-2-yl)ethan-1-amine

https://huagongshe.com/reaction/1249886

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantSodium HydroxideHCID 14798—
ReactantN-[1-(2-Naphthalenyl)ethyl]formamideHCID 18543124—
SolventWaterHCID 962—
Product1-(Naphthalen-2-yl)ethan-1-amineHCID 385714598.7%

Reaction Steps

A mixture of N-(1-naphthalen-2-yl-ethyl)-formamide (1.12 g), ethanol (10 mL) and 5 N sodium hydroxide (10 mL) is heated at reflux for 1 hour. The solution is cooled, poured into water and extracted with ether. The ether solution is dried with anhydrous potassium carbonate, filtered and concentrated to give the product (0.95 g) as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06335350B1
Source datasetuspto-grants-2002_01
ORD IDord-98d26a8bcef8466e8ded8509909d6a25
Source noteuspto-grants-2002_01