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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1249900Generated: October 26, 2026

1-(4-Fluorophenyl)-2-methylpropan-1-ol → 1-(4-Fluorophenyl)-2-methylpropan-1-one

https://huagongshe.com/reaction/1249900

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)-2-methylpropan-1-olHCID 10419564—
ReactantJones' reagentHCID 131709961—
SolventAcetoneHCID 180—
Product1-(4-Fluorophenyl)-2-methylpropan-1-oneHCID 2782829—

Reaction Steps

To a solution of 1-(4-Fluoro-phenyl)-2-methyl-propan-1-ol (1.6 g) in acetone (10 mL) at 0° C. is added Jones reagent (20 mL) with stirring. After 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol. Diethyl ether is added followed by anhydrous magnesium and the mixture is filtered and evaporated to give the product, a yellow oil (1.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06335350B1
Source datasetuspto-grants-2002_01
ORD IDord-10312aa0924a4933be3b8bdc38e2d596
Source noteuspto-grants-2002_01