Butylamine → HCID 131723077, compound

HRID 1249940Notes

Reaction equation

HRID 1249940 reaction equation
[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH2:26][CH3:27])[C:10]([N:12]1[C:20]2[C:15](=[C:16]([Cl:22])[C:17]([Cl:21])=[CH:18][CH:19]=2)[CH2:14][CH:13]1[C:23]([OH:25])=O)=[O:11])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:28]([NH2:32])[CH2:29][CH2:30][CH3:31]>>[CH2:28]([NH:32][C:23]([CH:13]1[CH2:14][C:15]2[C:20](=[CH:19][CH:18]=[C:17]([Cl:21])[C:16]=2[Cl:22])[N:12]1[C:10](=[O:11])[C@@H:9]([NH:8][C:6]([O:5][C:1]([CH3:3])([CH3:2])[CH3:4])=[O:7])[CH2:26][CH3:27])=[O:25])[CH2:29][CH2:30][CH3:31]

Participants

3

Reactant 2

HCID 8007ButylamineHCID 131723078HCID 131723078, compound

Product 1

HCID 131723077HCID 131723077, compound

Procedure

This compound was prepared from 1-(N-t-butoxycarbonyl-2-(S)-aminobutyryl)-4,5-dichloroindoline-2-(R/S)-carboxylic acid as described in Example 1, using butylamine instead of trifluoroethylamine hydrochloride.

Sources & evidence

ORD record
ord-735fbe41494b47f290f2539fa054294e
Source dataset
uspto-grants-2002_01
Patent number
US06335360B1

Reaction notes

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