Ethanol → HCID 18329037, compound

Participants

Reaction Conditions

Reaction Steps

Sodium pieces (5.15 g, 240 mmol) were added in portions to ethanol (157 ml). The resulting solution was cooled in an ice/acetone bath to −15° C. and then over one hour a mixture of 2-methylbenzaldehyde (7.209 g, 60 mmol) and ethyl azidoacetate (30.980 g, 240 mmol) was added at a rate that maintained the temperature below 10° C. After 3 hours, the solution was stored at 5° C. for two days to give pure product as yellow crystals.

Provenance & Evidence