3-(4-oxocyclohexyl)-1H-indole-5-carbonitrile → 8-{4-[4-(5-Cyano-1H-indol-3-yl)-cyclohexyl]-[1,4]diazepan-1-yl}-quinoline

関与物質

反応手順

The title compound was prepared according to Example 3, Step 4 except that 8-[1,4]diazepan-1-yl-quinoline was used instead of 1-(2-methoxy-phenyl)-[1,4]diazepane and 3-(4-oxo-cyclohexyl)-1H-indole-5-carbonitrile was used in place of 4-(5-fluoro-1H-3-indolyl)-cyclohexanone. Yield: 92%; MS (ES) m/z (relative intensity): 450 (M++H, 100).

情報源と証拠