4-(6-Fluoro-1H-indol-3-YL)cyclohexanone → 8-{4-[4-(6-Fluoro-1H-indol-3-yl)-cyclohexyl]-[1,4]diazepan-1-yl}-quinoline

Participants

Reaction Steps

The title compound was prepared according to Example 3, Step 4 except that 8-[1,4]diazepan-1-yl-quinoline was used instead of 1-(2-methoxy-phenyl)-[1,4]diazepane and 4-(6-fluoro-1H-indol-3-yl)-cyclohexanone was used in place of 4-(5-fluoro-1H-3-indolyl)-cyclohexanone. Yield: 89%; MS (ES) m/z (relative intensity): 443 (M++H, 100).

Provenance & Evidence