1-[3-(Trifluoromethyl)phenyl]-1,4-diazepane → 3-{4-[4-(3-Trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-cyclohexyl}-6-fluoro-1H-indole

Participants

Reaction Steps

The title compound was prepared according to Example 3, Step 4 except 1-(3-trifluoromethyl-phenyl)-[1,4]diazepane was used instead of 1-(2-methoxy-phenyl)-[1,4]diazepane and 4-(6-fluoro-1H-indol-3-yl)-cyclohexanone was used in place of 4-(5-fluoro-1H-3-indolyl)-cyclohexanone. Yield: 64%; MS (ES) m/z (relative intensity): 460 (M++H, 100).

Provenance & Evidence