Water → HCID 131723086, compound

Participants

Reaction Steps

To a solution of (4E)-N-methyl-5-(3,4-methylenedioxyphenyl)-4-penten-2-amine (228.7 mg, 1.043 mmol) in absolute ethanol (3.5 mL) was added galactaric acid (109.6 mg, 0.522 mmol). Water (1.2 mL) was added drop-wise while gently warming the solution. The solution was filtered through glass wool to remove a few insoluble particles, washing the filter plug with ethanol-water (4:1, v/v) (1 mL). The filtrate was diluted with ethanol (7 mL), cooled to ambient temperature, and further cooled at 5° C. for 18 h. The product was filtered, washed with cold ethanol, and vacuum dried at 40° C. to afford 292 mg (86.2%) of a white, crystalline powder, mp 172-176° C.

Provenance & Evidence