Water → HCID 131723089, compound

Participants

Reaction Conditions

Reaction Steps

In succession, galactaric acid (91 mg, 0.43 mmol) and water (0.4 mL) were added to a solution of (4E)-N-methyl-5-(4-methyl-3-nitrophenyl)-4-penten-2-amine (204 mg, 0.871 mmol) in methanol (4 mL). The mixture was warmed to 50° C. and filtered through a glass wool plug. The filtrate was diluted with ethanol (4 mL) and kept at −4° C. for 16 h. Filtration and vacuum drying at 40° C., gave 199 mg (68.2% yield) of yellow powder, mp 150-153° C.

Provenance & Evidence