Water → HCID 131723090, compound

Participants

Reaction Conditions

Reaction Steps

In succession, galactaric acid (95 mg, 0.45 mmol) and water (0.5 mL) were added to a solution of (4E)-N-methyl-5-(3-(dimethylamino)phenyl)-4-penten-2-amine (198 mg, 0.907 mmol) in methanol (4 mL). The mixture was warmed to 60° C. and filtered through a glass wool plug. The filtrate was diluted with ethanol (4 mL) and kept at −4° C. for 16 h. Filtration and vacuum drying at 40° C., gave 218 mg (74.9% yield) of white powder, mp 164-166° C.

Provenance & Evidence