HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dibromobutane → HCID 18328030, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 8-Methoxy-1,4-benzoxazepin-5(4H)-one | HCID 15542510 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18328030 | HCID 18328030 | — |
Reaction Steps
200 mg of 4,5-dihydro-8-methoxy-1,4-benzoxazepin-5-one was dissolved in 10 ml of dimethylformamide, then 50 mg (1.2 equivalents) of 60% sodium hydride was added under ice cooling. This was agitated for 30 minutes, then 790 mg (3 equivalents) of 1,4-dibromobutane was added and the resultant mixture was agitated at room temperature for 6 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06337397B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-41f2e0fb0c894f7a97dfef4276e884b8 |
| Source note | uspto-grants-2002_01 |