1,4-Dibromobutane → HCID 18327903, compound

Participants

Reaction Steps

2.0 g of 4,5-dihydro-3-methyl1,4-benzoxazepin-5-one was dissolved in 120 ml of dimethylformamide, then 548 mg (1.2 equivalents) of 60% sodium hydride was added under ice cooling. This was agitated at room temperature for 1 hour, then 4.1 ml (3 equivalents) of 1,4-dibromobutane was added and the resultant mixture was agitated for 3 hours.

Provenance & Evidence