Sodium borohydride → HCID 15490960, compound

HRID 1250310Notes

Reaction equation

HRID 1250310 reaction equation
[Cl-].[Cl:2][C:3]1[N:9]([CH2:10][CH2:11][CH2:12][CH:13]=[N+:14]2[CH:19]=[CH:18][C:17]([C:20]3[N:25]=[CH:24][CH:23]=[CH:22][N:21]=3)=[CH:16][CH2:15]2)[C:8](=[O:26])[C:7]2[CH:27]=[CH:28][CH:29]=[CH:30][C:6]=2[O:5][CH:4]=1.[BH4-].[Na+]>C(O)C>[Cl:2][C:3]1[N:9]([CH2:10][CH2:11][CH2:12][CH2:13][N:14]2[CH2:19][CH2:18][C:17]([C:20]3[N:21]=[CH:22][CH:23]=[CH:24][N:25]=3)=[CH:16][CH2:15]2)[C:8](=[O:26])[C:7]2[CH:27]=[CH:28][CH:29]=[CH:30][C:6]=2[O:5][CH:4]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 70103080HCID 70103080, compound

Product 1

HCID 15490960HCID 15490960, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

560 mg of the compound of Example 24 was dissolved in 15 ml of ethanol, 98 mg (2 equivalents) of sodium borohydride was added under ice cooling, then the resultant mixture was agitated at room temperature for 10 minutes.

Sources & evidence

ORD record
ord-7fa2f86bce4c4241a985fb3d067f42d4
Source dataset
uspto-grants-2002_01
Patent number
US06337397B1

Reaction notes

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