Hydrogen Sulfide → HCID 54486672, compound

HRID 1250389Notes

Reaction equation

HRID 1250389 reaction equation
[CH3:1][O:2][C:3]([C:5]1[N:6]([CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([C:25]#[N:26])[CH:20]=2)[C:7]2[C:12]([C:13]=1[C:14]([O:16][CH3:17])=[O:15])=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:4].[SH2:27]>>[CH3:1][O:2][C:3]([C:5]1[N:6]([CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[C:21]([C:25](=[S:27])[NH2:26])[CH:20]=2)[C:7]2[C:12]([C:13]=1[C:14]([O:16][CH3:17])=[O:15])=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:4]

Participants

3

Reactant 2

HCID 402Hydrogen SulfideHCID 11100129HCID 11100129, compound

Product 1

HCID 54486672HCID 54486672, compound

Procedure

The starting material 1-(3-thiocarbamoylphenyl)methyl-1H-indole-2,3-dicarboxylic acid dimethyl ester was prepared analogously to example 13/1 by reacting 1-(3-cyano-benzyl)-1H-indole-2,3-dicarboxylic acid dimethyl ester (example 11/1) with hydrogen sulfide. It was crystallized from ether/hexane to give yellow crystals with m.p. 176-178° C.

Workup

  1. customIt was crystallized from ether/hexane
  2. customto give yellow crystals with m.p. 176-178° C.

Sources & evidence

ORD record
ord-5bc3652f7792450a816a6b0499dac391
Source dataset
uspto-grants-2002_01
Patent number
US06337344B1

Reaction notes

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