HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 131723093, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Reactant | 1-Phenethylamine, (+)- | HCID 643189 | — |
| Reactant | HCID 10959912 | HCID 10959912 | — |
| Product | HCID 131723093 | HCID 131723093 | 73% |
Reaction Steps
This compound was prepared from 5-benzyloxy-1-(3-cyano-benzyl)-1H-indole-2-carboxylic acid and (R)-1-phenyl-ethyl-amine by using diphenylphosphoryl azide and diisopropylethylamine as described in example 3/1. The crude material was purified by flash chromatography on silica gel with dichloromethane to give the desired product in 73% yield. M.p. 169-170° C. MS: 486.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06337344B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-a08e1803e8df4531aba39e7321af44ab |
| Source note | uspto-grants-2002_01 |