HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → HCID 69780616, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Reactant | HCID 10891118 | HCID 10891118 | — |
| Product | HCID 69780616 | HCID 69780616 | 97% |
Reaction Steps
This compound was prepared from 1-(3-cyano-benzyl)-1H-indole-2-carboxylic acid (example 1/2) and benzylamine by using diphenylphosphoryl azide and diisopropylethylamine as described in example 3/1. The crude material was purified by flash chromatography on silica gel with toluene/ethanol 19:0.5 to give the desired product in 97% yield. M.p. 129-131° C. MS: 366.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06337344B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-1d84b32fed3a48d0be3f5333b3aea024 |
| Source note | uspto-grants-2002_01 |