HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 86757720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 86757721 | HCID 86757721 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86757720 | HCID 86757720 | 70% |
Reaction Steps
This compound was prepared from [4-({[1-(3-amidino-benzyl)-5-nitro-1H-indole-2-carbonyl]-amino}-methyl)-phenyl]-trimethyl-ammonium trifluoroacetate trifluoroacetic acid salt (example 36) by hydrogenation in ethanol with 3 equivalents of acetic acid, catalyzed by Pd/C (10%). Yield: 70%. M.p. 114° C. (dec.). MS: 455.3 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06337344B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-f863773e2a274bbbb04ab274813de13f |
| Source note | uspto-grants-2002_01 |